Alexander V. Chervonsky, MD

Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression.
Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688.
PMID: 39227386

Innate Immunity in Type 1 Diabetes.
Innate Immunity in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2024 Jul 29.
PMID: 39074873

Microbial influences on severity and sex bias of systemic autoimmunity.
Microbial influences on severity and sex bias of systemic autoimmunity. Immunol Rev. 2024 08; 325(1):64-76.
PMID: 38716867

Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ.
Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ. Viruses. 2023 01 29; 15(2).
PMID: 36851600

Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ.
Retroviral infection and commensal bacteria dependently alter the metabolomic profile in a sterile organ. bioRxiv. 2023 Jan 11.
PMID: 36711645

Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes.
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes. Cell Host Microbe. 2023 02 08; 31(2):213-227.e9.
PMID: 36603588

Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes.
Funsten MC, Yurkovetskiy LA, Kuznetsov A, Reiman D, Hansen CHF, Senter KI, Lee J, Ratiu J, Dahal-Koirala S, Antonopoulos DA, Dunny GM, Sollid LM, Serreze D, Khan AA, Chervonsky AV. Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes. Cell Host Microbe. 2022 Dec 28.
PMID: 36603588

Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus.
Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus. Cell Rep. 2022 09 13; 40(11):111341.
PMID: 36103821

Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice.
Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice. iScience. 2022 May 20; 25(5):104241.
PMID: 35494242

Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68.
Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68. J Immunol. 2021 12 15; 207(12):2944-2951.
PMID: 34810225