People

Angela M Lager, PhD

Dr. Lager’s research and clinical interests are focused on using clinical cytogenetic and molecular genetic modalities for the investigation and discovery of neoplasm-associated genetic abnormalities. She’s interested in employing sophisticated clinical laboratory diagnostics toward discovery of novel disease markers, and using these markers for patient prognosis and treatment stratification.

University of Wisconsin-Madison
Madison, WI
Fellowship - Clinical Molecular Genetics and Genomics
2018

University of Wisconsin-Madison
Madison, WI
Fellowship - Clinical Cytogenetics and Genomics
2017

Case Western Reserve University
Cleveland, OH
PhD - Genetics
2015

Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults.
Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults. Blood Adv. 2024 01 09; 8(1):164-171.
PMID: 38039510

Germline loss-of-function BRCA1 and BRCA2 mutations and risk of de novo hematopoietic malignancies.
Germline loss-of-function BRCA1 and BRCA2 mutations and risk of de novo hematopoietic malignancies. Haematologica. 2024 Jan 01; 109(1):351-356.
PMID: 37139596

Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis.
Acute lymphoblastic leukemia with myeloid mutations is a high-risk disease associated with clonal hematopoiesis. Blood Cancer Discov. 2023 Dec 27.
PMID: 38150184

Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults.
Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults. Blood Adv. 2023 Dec 01.
PMID: 38039510

Postmortem genetic testing in sudden unexplained death: A public health laboratory experience.
Postmortem genetic testing in sudden unexplained death: A public health laboratory experience. J Forensic Sci. 2023 Nov; 68(6):2065-2075.
PMID: 37614113

Germline loss of function BRCA1 and BRCA2 mutations and risk of de novo hematopoietic malignancies.
Germline loss of function BRCA1 and BRCA2 mutations and risk of de novo hematopoietic malignancies. Haematologica. 2023 May 04.
PMID: 37139596

TP53/PLCG2-mutated diffuse large B-cell lymphoma richter transformation (DLBCL-RT) of CLL with unusual CD2 and PD-1 expression.
TP53/PLCG2-mutated diffuse large B-cell lymphoma richter transformation (DLBCL-RT) of CLL with unusual CD2 and PD-1 expression. Leuk Lymphoma. 2022 11; 63(11):2735-2738.
PMID: 35719104

MUC4 expression by immunohistochemistry is a specific marker for BCR-ABL1+ and BCR-ABL1-like B-lymphoblastic leukemia.
MUC4 expression by immunohistochemistry is a specific marker for BCR-ABL1+ and BCR-ABL1-like B-lymphoblastic leukemia. Leuk Lymphoma. 2022 06; 63(6):1436-1444.
PMID: 35171727

CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.
CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer. Sci Rep. 2021 10 08; 11(1):20059.
PMID: 34625620

Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel. Sci Transl Med. 2021 Sep 08; 13(610):eabd4811.
PMID: 34516829

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