Dr. Maneesh Kumar Misra, MS, PhD, F(ACHI) is an Associate Medical Director of Transplant Immunology and Immunogenetics Section, and the Assistant Professor of Clinical Pathology. He is certified by the American College of Histocompatibility and Immunogenetics. His research and scholarly interests include allogeneic transplantation, autoimmunity, hematopoietic stem cell transplantation, immunogenetics, and solid organ transplantation. His research mainly focuses on the detection and functional characterization of alloantibodies in the setting of clinical allogenic transplantation. He has identified and characterized several novel HLA alleles, authored more than 20 peer-reviewed publications, and coauthored a book. Maneesh received his PhD from Banaras Hindu University Institute of Medical Sciences in India, and subsequently held research positions at the Sanjay Gandhi Postgraduate Institute of Medical Sciences. He then completed a postdoctoral fellowship at the University of California, San Francisco School of Medicine, and an American Society for Histocompatibility and Immunogenetics approved Director-in-training clinical fellowship in transplant immunology and immunogenetics at the University of Chicago Pritzker School of Medicine.
The University of Chicago Medicine
Chicago, IL, USA
Clinical Fellowship - Transplant Immunology and Immunogenetics
2020
University of California San Francisco School of Medicine
San Francisco, CA, USA
Postdoctoral Fellowship - Immunology and Immunogenetics
2018
Banaras Hindu University, Institute of Medical Sciences
Varanasi, UP, India
Ph.D. - Transplant Immunology and Immunogenetics
2015
Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01.
Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA. 2024 Feb; 103(2):e15368.
PMID: 38342772
Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco.
Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco. Front Biosci (Schol Ed). 2023 11 27; 15(4):13.
PMID: 38163953
Exceptional diversity of KIR and HLA class I in Egypt.
Exceptional diversity of KIR and HLA class I in Egypt. HLA. 2024 Jan; 103(1):e15177.
PMID: 37528739
Spherotech-EDTA combined serum treatment reduces background more effectively as compared to One Lambda Adsorb Out™ and LIFECODES Serum Cleaner in Luminex-based solid-phase immunoassays for HLA antibody detection.
Spherotech-EDTA combined serum treatment reduces background more effectively as compared to One Lambda Adsorb Out™ and LIFECODES Serum Cleaner in Luminex-based solid-phase immunoassays for HLA antibody detection. HLA. 2023 Aug; 102(2):147-156.
PMID: 36961354
A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain.
A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Immunology. 2021 02; 162(2):194-207.
PMID: 32986852
Effective desensitization for a strong donor-specific HLA antibody in a case of HLA-mismatched allogeneic hematopoietic cell transplantation.
Effective desensitization for a strong donor-specific HLA antibody in a case of HLA-mismatched allogeneic hematopoietic cell transplantation. HLA. 2019 09; 94(3):307-311.
PMID: 31314169
A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.
A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7419-7424.
PMID: 30910980
Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.
Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop. Hum Immunol. 2018 Dec; 79(12):825-833.
PMID: 30321631
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis.
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. Genes Immun. 2019 01; 20(1):46-55.
PMID: 29362509
The immunogenetics of neurological disease.
The immunogenetics of neurological disease. Immunology. 2018 04; 153(4):399-414.
PMID: 29159928
CAP/BSD Travel Award
University of Chicago
2019
Readers' Choice: The Best Paper of Genes and Immunity
Genes and Immunity Journal
2018
Immunology Review Honorarium
British Society for Immunology
2018
Best Poster Award in Most Innovative Research Category
American Society for Histocompatibility and Immunogenetics
2017