Dr. Chang specializes in renal pathology. He joined the Department of Pathology at the University of Chicago in 2004 and is now a Professor. He was Past-President of the Renal Pathology Society (2017) and Chicago Pathology Society (2011-2013). He has taught more than 30 educational courses at the annual meetings for the American Society Clinical Pathology, College of American Pathologists, US & Canadian Academy of Pathology, American Society of Nephrology, American College of Rheumatology, and American Urological Association.
His research interests include the role of B and plasma cells in lupus nephritis and transplant rejection. He is on the editorial board of Laboratory Investigation and Archives of Pathology and Laboratory Medicine. He has authored over 100 peer-reviewed papers, reviews, and book chapters, including the Kidney chapter for Robbins and Cotran: Pathologic Basis of Disease. He is the co-editor of the 2nd edition of the “Diagnostic Pathology: Transplant Pathology” textbook and co-editor for the 3rd edition of “Diagnostic Pathology: Kidney Diseases.”
University of Washington Medical Center
Fellowship - Renal Pathology
2004
University of Washington Medical Center
Residency - Anatomic and Clinical Pathology
2003
Albany Medical College
MD
1999
MIT
BA
1995
Renal Vasculitis and Pauci-immune Glomerulonephritis Associated With Immune Checkpoint Inhibitors.
Gallan AJ, Alexander E, Reid P, Kutuby F, Chang A, Henriksen KJ. Renal Vasculitis and Pauci-immune Glomerulonephritis Associated With Immune Checkpoint Inhibitors. Am J Kidney Dis. 2019 12; 74(6):853-856.
PMID: 31204194
Quantifying in situ adaptive immune cell cognate interactions in humans.
Liarski VM, Sibley A, van Panhuys N, Ai J, Chang A, Kennedy D, Merolle M, Germain RN, Giger ML, Clark MR. Quantifying in situ adaptive immune cell cognate interactions in humans. Nat Immunol. 2019 04; 20(4):503-513.
PMID: 30778242
Collapsing Glomerulopathy in Lambda Light Chain Amyloidosis: A Report of 2 Cases.
Khalighi MA, Gallan AJ, Chang A, Meehan SM. Collapsing Glomerulopathy in Lambda Light Chain Amyloidosis: A Report of 2 Cases. Am J Kidney Dis. 2018 10; 72(4):612-616.
PMID: 29908693
Thromboprophylaxis in Spinal Surgery.
Mosenthal WP, Landy DC, Boyajian HH, Idowu OA, Shi LL, Ramos E, Lee MJ. Thromboprophylaxis in Spinal Surgery. Spine (Phila Pa 1976). 2018 04 15; 43(8):E474-E481.
PMID: 23262784
Bowman capsulitis predicts poor kidney allograft outcome in T cell-mediated rejection.
Gallan AJ, Chon WJ, Josephson MA, Cunningham PN, Henriksen KJ, Chang A. Bowman capsulitis predicts poor kidney allograft outcome in T cell-mediated rejection. Hum Pathol. 2018 06; 76:47-51.
PMID: 29501487
Kidney Transplant Outcomes in 2 Adults With Down Syndrome.
Henriksen KJ, Chang A, Bayliss GP. Kidney Transplant Outcomes in 2 Adults With Down Syndrome. Kidney Int Rep. 2018 Jul; 3(4):979-984.
PMID: 29988986
The Banff Working Group Classification of Definitive Polyomavirus Nephropathy: Morphologic Definitions and Clinical Correlations.
Nickeleit V, Singh HK, Randhawa P, Drachenberg CB, Bhatnagar R, Bracamonte E, Chang A, Chon WJ, Dadhania D, Davis VG, Hopfer H, Mihatsch MJ, Papadimitriou JC, Schaub S, Stokes MB, Tungekar MF, Seshan SV. The Banff Working Group Classification of Definitive Polyomavirus Nephropathy: Morphologic Definitions and Clinical Correlations. J Am Soc Nephrol. 2018 02; 29(2):680-693.
PMID: 29279304
Cetuximab-Associated Crescentic Diffuse Proliferative Glomerulonephritis.
Manthri S, Bandaru S, Chang A, Hudali T. Cetuximab-Associated Crescentic Diffuse Proliferative Glomerulonephritis. Case Rep Nephrol. 2017; 2017:7964015.
PMID: 29348949
Bim suppresses the development of SLE by limiting myeloid inflammatory responses.
Tsai F, Homan PJ, Agrawal H, Misharin AV, Abdala-Valencia H, Haines GK, Dominguez S, Bloomfield CL, Saber R, Chang A, Mohan C, Hutcheson J, Davidson A, Budinger GRS, Bouillet P, Dorfleutner A, Stehlik C, Winter DR, Cuda CM, Perlman H. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. J Exp Med. 2017 Dec 04; 214(12):3753-3773.
PMID: 29114065
Medical renal diseases are frequent but often unrecognized in adult autopsies.
Perrone ME, Chang A, Henriksen KJ. Medical renal diseases are frequent but often unrecognized in adult autopsies. Mod Pathol. 2018 02; 31(2):365-373.
PMID: 28984299