Dr. Chang specializes in renal pathology. He joined the Department of Pathology at the University of Chicago in 2004 and is now a Professor. He was Past-President of the Renal Pathology Society (2017) and Chicago Pathology Society (2011-2013). He has taught more than 30 educational courses at the annual meetings for the American Society Clinical Pathology, College of American Pathologists, US & Canadian Academy of Pathology, American Society of Nephrology, American College of Rheumatology, and American Urological Association.
His research interests include the role of B and plasma cells in lupus nephritis and transplant rejection. He is on the editorial board of Laboratory Investigation and Archives of Pathology and Laboratory Medicine. He has authored over 100 peer-reviewed papers, reviews, and book chapters, including the Kidney chapter for Robbins and Cotran: Pathologic Basis of Disease. He is the co-editor of the 2nd edition of the “Diagnostic Pathology: Transplant Pathology” textbook and co-editor for the 3rd edition of “Diagnostic Pathology: Kidney Diseases.”
University of Washington Medical Center
Fellowship - Renal Pathology
2004
University of Washington Medical Center
Residency - Anatomic and Clinical Pathology
2003
Albany Medical College
MD
1999
MIT
BA
1995
Collapsing Glomerulopathy and Thrombotic Microangiopathy after Chimeric Antigen Receptor T Cell Therapy.
Collapsing Glomerulopathy and Thrombotic Microangiopathy after Chimeric Antigen Receptor T Cell Therapy. Kidney360. 2026 Sep 04.
PMID: 42696386
A Pre-Kidney Transplant Blood-Based Next-Generation Sequencing Assay to Predict Early Acute Rejection.
A Pre-Kidney Transplant Blood-Based Next-Generation Sequencing Assay to Predict Early Acute Rejection. Kidney360. 2026 Aug 01; 7(8):1792-1806.
PMID: 42133442
Transcription factor 21 deletion from podocyte precursors as a model for congenital nephrotic syndrome.
Transcription factor 21 deletion from podocyte precursors as a model for congenital nephrotic syndrome. Am J Physiol Renal Physiol. 2026 06 01; 330(6):F746-F760.
PMID: 42090190
A Rare Case of Seronegative anti-Glomerular Basement Membrane Disease with Pulmonary Involvement.
A Rare Case of Seronegative anti-Glomerular Basement Membrane Disease with Pulmonary Involvement. R I Med J (2013). 2026 Apr 01; 109(4):52-54.
PMID: 41886661
The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning.
The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning. Am J Transplant. 2026 May; 26(5):922-936.
PMID: 41888020
High-dimensional spatial proteomics and novel machine learning pipeline identifies disease specific renal damage states.
High-dimensional spatial proteomics and novel machine learning pipeline identifies disease specific renal damage states. bioRxiv. 2026 Jan 15.
PMID: 41648405
Responsible adoption of multimodal artificial intelligence in health care: promises and challenges.
Responsible adoption of multimodal artificial intelligence in health care: promises and challenges. Lancet Digit Health. 2025 Dec; 7(12):100917.
PMID: 41387134
Greater value add from electronic health records than polygenic risk scores for predicting myocardial infarction in machine learning.
Greater value add from electronic health records than polygenic risk scores for predicting myocardial infarction in machine learning. Commun Med (Lond). 2025 Nov 03; 5(1):450.
PMID: 41184489
A 16-Year-Old With a Hypertension Emergency: A Quiz.
A 16-Year-Old With a Hypertension Emergency: A Quiz. Am J Kidney Dis. 2025 Oct; 86(4):A13-A16.
PMID: 40976636
The Nephrologist's Perspective in Evaluation and Management of Localized Renal Masses: Core Curriculum 2025.
The Nephrologist's Perspective in Evaluation and Management of Localized Renal Masses: Core Curriculum 2025. Am J Kidney Dis. 2025 Nov; 86(5):690-701.
PMID: 40910966