Dr. Chang specializes in renal pathology. He joined the Department of Pathology at the University of Chicago in 2004 and is now a Professor. He was Past-President of the Renal Pathology Society (2017) and Chicago Pathology Society (2011-2013). He has taught more than 30 educational courses at the annual meetings for the American Society Clinical Pathology, College of American Pathologists, US & Canadian Academy of Pathology, American Society of Nephrology, American College of Rheumatology, and American Urological Association.
His research interests include the role of B and plasma cells in lupus nephritis and transplant rejection. He is on the editorial board of Laboratory Investigation and Archives of Pathology and Laboratory Medicine. He has authored over 100 peer-reviewed papers, reviews, and book chapters, including the Kidney chapter for Robbins and Cotran: Pathologic Basis of Disease. He is the co-editor of the 2nd edition of the “Diagnostic Pathology: Transplant Pathology” textbook and co-editor for the 3rd edition of “Diagnostic Pathology: Kidney Diseases.”
University of Washington Medical Center
Fellowship - Renal Pathology
2004
University of Washington Medical Center
Residency - Anatomic and Clinical Pathology
2003
Albany Medical College
MD
1999
MIT
BA
1995
Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression.
Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688.
PMID: 39227386
Large lysosomes in Chédiak-Higashi syndrome.
Large lysosomes in Chédiak-Higashi syndrome. Kidney Int. 2024 Aug; 106(2):320.
PMID: 39032971
Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data.
Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data. bioRxiv. 2024 Jan 11.
PMID: 38260318
The Detrimental Impact of End-Stage Kidney Disease Is Not Reflected in Autopsy Reports.
The Detrimental Impact of End-Stage Kidney Disease Is Not Reflected in Autopsy Reports. Arch Pathol Lab Med. 2024 Jan 01; 148(1):74-77.
PMID: 37014976
Podocyte injury at young age causes premature senescence and worsens glomerular aging.
Podocyte injury at young age causes premature senescence and worsens glomerular aging. Am J Physiol Renal Physiol. 2024 01 01; 326(1):F120-F134.
PMID: 37855038
Molecular architecture of proliferative lupus nephritis as elucidated using 50-plex imaging mass cytometry proteomics.
Molecular architecture of proliferative lupus nephritis as elucidated using 50-plex imaging mass cytometry proteomics. Clin Immunol. 2023 09; 254:109713.
PMID: 37516396
Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.
Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span. Aging (Albany NY). 2023 07 23; 15(14):6658-6689.
PMID: 37487005
An International Survey of Genitourinary and Renal Pathologists Regarding Evaluation of the Non-Neoplastic Parenchyma in Kidney Cancer Specimens.
An International Survey of Genitourinary and Renal Pathologists Regarding Evaluation of the Non-Neoplastic Parenchyma in Kidney Cancer Specimens. Int J Surg Pathol. 2024 Apr; 32(2):273-278.
PMID: 37226477
The Detrimental Impact of End-Stage Kidney Disease Is Not Reflected in Autopsy Reports.
The Detrimental Impact of End-Stage Kidney Disease Is Not Reflected in Autopsy Reports. Arch Pathol Lab Med. 2023 Apr 05.
PMID: 37014976
Artificial Intelligence in Congenital Heart Disease: Current State and Prospects.
Artificial Intelligence in Congenital Heart Disease: Current State and Prospects. JACC Adv. 2022 Dec; 1(5):100153.
PMID: 38939457